Dr. David Smith, DVM, PhD

Titles:

Endowed Professor
Mikell and Mary Cheek Hall Davis Endowment for Beef Cattle Health and Reproduction

Contacts:

drs198@msstate.edu
Office: (662) -32-5-13

Overview

Summary:

As an epidemiologist, I have studied the cause, control, and prevention of diseases of cattle important to human and cattle health. My contributions to science have the central theme of creating teams of investigators to discover how food animal production-systems can be modified to improve the health, well-being, and productivity of animals (primarily cattle), and also benefit human and environmental health.

Education:

Doctor of Philosophy (Ph.D.), Veterinary Preventive Medicine, Ohio State University, The, 1997
Doctor of Veterinary Medicine (D.V.M.), Veterinary Medicine, Ohio State University, The, 1983
Bachelor of Science (B.S.), Agriculture, Ohio State University, The, 1980

Research interests:

Applying systems thinking to solve common health and productivity problems of cattle, including:

antimicrobial resistance
bovine respiratory disease
failure of transfer of maternal immunity
pre-harvest food safety

Publications

Conference Proceeding

Identification of potential predictive biomarkers and molecular mechanisms contributing to BRD-associated mortality in post-weaned beef cattle. World Buiatrics Congress. 2022
Sorry, but this cow is open, too: investigating and monitoring reproduction.. Academy of Veterinary Consultants. 2022
Understanding the nature of epidemics and how to quell them. . Convention of the American Veterinary Medical Association. 2022
A simulation model to study the effects of dog density on illness and release rates in animal shelters. . International Symposium of Veterinary Epidemiology and Economics. 2022
The effect of removing arrival metaphylaxis on the pre-harvest beef value chain.. International Symposium of Veterinary Epidemiology and Economics. 2022
Case-control study to identify management practices associated with morbidity and mortality from bovine anaplasmosis in Mississippi USA cow-calf herds.. International Symposium of Veterinary Epidemiology and Economics. 2022
Multipopulational transcriptomic analysis of high-risk beef cattle on arrival reveals genes and mechanisms which may predict bovine respiratory disease. American Association of Bovine Practitioners. 2021
Increased expression of viral defense genes at arrival may contribute to BRD-associated mortality. Conference of Research Workers in Animal Diseases . 2019
Whole blood RNA-seq analysis at arrival to identify biomarkers of respiratory disease risk in stocker cattle. Conference of Research Workers in Animal Diseases . 2019
Whole blood RNA-Seq analysis of stocker calves reveals insights into BRD. Conference of Research Workers in Animal Diseases . 2019
Whole blood RNA-Seq analysis of stocker calves at arrival provides immunological and metabolic distinction related to BRD. 2019 Bovine Respiratory Disease Symposium . 2019
Whole blood transcriptome analysis reveals altered pathways related to inflammation and fatty acid metabolism in stocker calves that develop bovine respiratory disease. International Veterinary Immunology Symposium . 2019
On-arrival blood transcriptomes identify altered immune pathways in stocker cattle that develop bovine respiratory disease. American College of Veterinary Internal Medicine Forum . 2019
Assesment of On-Arrival Vaccination and Deworming on Stocker Cattle Health and Growth Performance. Journal of Animal Science. 2018
Effect of crude protein levels and metaphylaxis on feedlot and carcass performance. Southern Section Animal Science. 2015

Journal Article

Failed transfer of passive immunity is a component cause of pre-weaning disease in beef and dairy calves: A systematic review and meta-analysis. . Bovine Practitioner. Volume 56, Issue 2, Pages 47-61. 2022
Survey of veterinary involvement in cattle health and production record-keeping on U.S. cow-calf operations.. Bovine Practitioner . Volume 56, Issue 2, Pages 29-37. 2022
Sources of variance in the results of a commercial bovine immunoglobulin G radial immunodiffusion assay.. J Diagn Invest / Intl Symp Vet Epidemiology Economics. 2022
Survey of U.S. cow-calf producer access to and use of technology for cattle health and production record-keeping purposes. Bovine Practitioner / Intl Symp Vet Epidemiology Economics. Volume 56, Issue 2, Pages 16-28. 2022
Survey of U.S. cow-calf producer methods and opinions of cattle health and production record-keeping. . Bovine Practitioner / Intl Symp Vet Epidemiology Economics. Volume 56, Issue 2, Pages 1-15. 2022
Multipopulational transcriptome analysis of post-weaned beef cattle at arrival further validates candidate biomarkers for predicting clinical bovine respiratory disease. Scientific Reports. Volume 11, Issue 1, Page 23877. 2021
Comprehensive at-arrival transcriptomic analysis of post-weaned beef cattle uncovers type I interferon and antiviral mechanisms associated with bovine respiratory disease mortality.. PloS one. Volume 16, Issue 4, Page e0250758. 2021
Factors associated with shelter dog euthanasia versus live release by adoption or transfer in the United States. Animals. Volume 11, Issue 4. 2021
The Number of Dogs Entering Shelters in Five States, and Factors that Affect Their Outcomes: A Study of the Sheltering System. Journal of Applied Animal Welfare Science. Volume 24, Issue 1, Pages 1-15. 2021
Phenotypic characteristics associated with shelter dog adoption in the United States. Animals. Volume 10, Issue 11, Pages 1-12. 2020
Factors associated with rabies vaccination of dog shelter staff in the United States. Zoonoses and Public Health. Volume 67, Issue 6, Pages 708-712. 2020
An Estimate of the Number of Dogs in US Shelters in 2015 and the Factors Affecting Their Fate. Journal of Applied Animal Welfare Science. Volume 23, Issue 3, Pages 302-314. 2020
Whole blood transcriptomic analysis of beef cattle at arrival identifies potential predictive molecules and mechanisms that indicate animals that naturally resist bovine respiratory disease. PLoS ONE. Volume 15, Issue 1. 2020
Sharp transection of the suspensory ligament as an alternative to digital strumming during canine ovariohysterectomy. Veterinary Surgery. Volume 48, Issue 2, Pages 216-221. 2019
Multidrug resistant Mannheimia haemolytica isolated from high-risk beef stocker cattle after antimicrobial metaphylaxis and treatment for bovine respiratory disease. Veterinary Microbiology. Volume 221, Pages 143-152. 2018
A randomized controlled trial to test the effect of on-arrival vaccination and deworming on stocker cattle health and growth performance. Bovine Practioner. Volume 52, Issue 1. 2018
Detection of Antigenic Variants of Swine Subtype H3 Influenza A Viruses from Clinical Samples. Journal of Clinical Microbiology. Pages JCM. 02049-16. 2017
The REFLECT Statement: Methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safety. Journal of Swine Health and Production. Volume 18, Issue 1, Pages 18-26. 2010
The REFLECT statement: methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safety. Prev Vet Med. Volume 93, Issue 1, Pages 11-8. 2010
The REFLECT statement: methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safety. J Vet Intern Med. Volume 24, Issue 1, Pages 57-64. 2010
The REFLECT statement: methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safety by modifying the CONSORT statement. Zoonoses Public Health. Volume 57, Issue 2, Pages 95-104. 2010

Published Abstract

Describing the consumption of chlortetracycline-containing mineral offered free-choice to commercial beef cows on pasture. MSU Undergraduate Research Symposium. Issue Spring 2023. 2023
Describing the consumption of chlortetracycline-containing mineral offered free-choice to commercial beef cows on pasture. Mississippi State University Undergraduate Research and Creative Discovery. 2023

Presentations

Abstract

"Effect of crude protein levels and metaphylaxis on feedlot and carcass performance." 2015 Southern Section Animal Science Meeting, ASAS, Atlanta, GA. 2015

Oral Presentation

"Identification of potential predictive biomarkers and molecular mechanisms contributing to BRD-associated mortality in post-weaned beef cattle." World Buiatrics Congress, WBC, Madrid, Spain. 2022
"Multipopulational transcriptomic analysis of high-risk beef cattle on arrival reveals genes and mechanisms which may predict bovine respiratory disease." Conference of the American Association of Bovine Practitioners (AABP), AABP, Salt Lake City, UT. 2021
"A system dynamics model of shelter capacity for care." Conference for Research Workers in Animal Disease, Conference for Research Workers in Animal Disease , Chicago, IL. 2020
"Economic Impact of Removing Arrival Metaphylaxis in the U.S. Stocker and Feedlot Industry." Conference for Research Workers in Animal Disease , Conference for Research Workers in Animal Disease , Chicago. 2020
"Exploring state-level risks for introducing chronic wasting disease into wild cervid populations." Conference for Research Workers in Animal Disease , Conference for Research Workers in Animal Disease , Chicago, IL. 2020
"A system dynamics model of shelter capacity for care." Conference of Research Workers in Animal Diseases, , Virtual. 2020
"Blood biomarker discovery in high-risk stocker cattle at-arrival: differentiating respiratory health and disease.." Conference of Research Workers in Animal Diseases(CRWAD) , CRWAD, Virtual. 2020
"Transcriptomic profiling of BRD-attributed mortality in stocker cattle identifies active inflammatory and antiviral pathways at arrival.." Conference of the American Association of Bovine Practitioners (AABP), AABP, Virtual. 2020

Poster

"Describing consumption of chlotetracycline-containing mineral offered free-choice to fall-calving cows on pasture: a pilot study." North MS Producer Advisor Council, NMREC, Verona. 2023

Areas of Expertise

Epidemiology cattle population medicine one health food safety veterinary medicine