Dr. Michail Panagiotidis PhD
Title:
- Professor and Department Head
Contacts:
mp2358@msstate.edu
Office: (662) 325-1130
R1000A
Visit Website for Michail Panagiotidis
Overview
Summary:
Professional Experience:
01/2025-present: Professor & Department Head
Department of Comparative Biomedical Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi, USA
11/2019-12/2024: Senior Scientist & Department Head
Department of Cancer Genetics, Therapeutics & Ultrastructural Pathology, Cyprus Institute of Neurology & Genetics, Nicosia, CYPRUS
09/2016-10/2019: Professor
Department of Applied Sciences, Faculty of Health & Life Sciences, Northumbria University, Newcastle Upon Tyne, England, UK
01/2013-08/2016: Professor & Chair
School of Life Sciences, Heriot Watt University, Edinburgh, Scotland, UK
01/2012-12/2012: Assistant Professor
Department of Pathological Anatomy, University of Ioannina, Medical School, Ioannina, GREECE
07/2009-06/2011: Adjunct Assistant Professor
School of Community Health Sciences, University of Nevada-Reno, Nevada, USA
07/2007-06/2009: Assistant Professor
School of Community Health Sciences, University of Nevada-Reno, Nevada, USA
08/2006-06/2007: Research Assistant Professor
Department of Nutrition, School of Global Public Health, University of North Carolina-Chapel Hill, North Carolina, USA
07/2004-07/2006: IRTA Postdoctoral Fellow
Laboratory of Signal Transduction, National Institute of Environmental Health Sciences (NIEHS/NIH), North Carolina, USA
Education:
- Doctor of Philosophy, Toxicoloy, University of Colorado-Denver, 2004
Research interests:
Multidisciplinary research in several areas of academic and industrial interests:
A. Cancer Therapeutics: Understanding the genetic/epigenetic background in cancer pathophysiology, development of translational cancer therapeutics and the role of phytochemicals in clinical adjuvant therapeutic strategies.
B. One Health Initiative: Environmental contamination, disease emergence / re-emergence and global health, personalised nutrition and chronic disease prevention.
C. Circular Economy: Health-promoting properties of sustainable and eco-friendly biomolecules towards the development of end user applications / consumer product formulations.
D. Biomedical Engineering: Biocompatibility and functional performance of novel engineered materials for orthopaedic implants, drug delivery platforms, etc.
Publications
Editorial
- Cancer epigenetics as biomarkers of clinical significance.. Cancer letters. Volume 342, Issue 2, Pages 168-9. 2014
- Biomarkers of oxidative stress and cancer: from chemistry, biology to clinical applications and personalized therapy.. Current molecular medicine. Volume 12, Issue 6, Pages 653-4. 2012
- Cell death or survival: The double-edged sword of environmental and occupational toxicity.. Chemico-biological interactions. Volume 188, Issue 2, Pages 265-6. 2010
- Environmental toxicity, oxidative stress, human disease and the "black box" of their synergism: how much have we revealed?. Mutation research. Volume 674, Issue 1-2, Pages 1-2. 2009
- Reactive oxygen species (ROS) in multistage carcinogenesis.. Cancer letters. Volume 266, Issue 1, Pages 3-5. 2008
Journal Article
- Concurrent Biocompatibility and Antimicrobial Functionality of Soft Diamond-Like Carbon Coating for Healthcare Applications.. Advanced healthcare materials. Volume 14, Issue 19, Page e2501224. 2025
- Exogenous Hormones, Tumor Intrinsic Subtypes, and Breast Cancer.. JAMA network open. Volume 8, Issue 7, Page e2519236. 2025
- Stbd1 stimulates AMPK signaling and alleviates insulin resistance in an in vitro hepatocyte model.. The FEBS journal. Volume 292, Issue 11, Pages 2882-2901. 2025
- Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification.. Nature communications. Volume 16, Issue 1, Page 4852. 2025
- Evaluating the Chemical Composition and Antitumor Activity of Origanum vulgare ssp. hirtum Essential Oil in a Preclinical Colon Cancer Model.. International journal of molecular sciences. Volume 26, Issue 10. 2025
- Overlap of high-risk individuals across family history, genetic & non-genetic breast cancer risk models: Analysis of 180,398 women from European & Asian ancestries.. medRxiv : the preprint server for health sciences. 2025
- Isothiocyanates Enhance the Anti-Melanoma Effect of Zebularine Through Modulation of Apoptosis and Regulation of DNMTs' Expression, Chromatin Configuration and Histone Posttranslational Modifications Associated with Altered Gene Expression Patterns.. Epigenomes. Volume 9, Issue 1. 2025
- Chemical Characterization and Assessment of the Neuroprotective Potential of Euphrasia officinalis.. International journal of molecular sciences. Volume 25, Issue 23. 2024
- Naturally-derived phenethyl isothiocyanate modulates apoptotic induction through regulation of the intrinsic cascade and resulting apoptosome formation in human malignant melanoma cells.. Toxicology mechanisms and methods. Volume 34, Issue 9, Pages 985-999. 2024
- Exploring the Role and Pathophysiological Significance of Aldehyde Dehydrogenase 1B1 (ALDH1B1) in Human Lung Adenocarcinoma.. International journal of molecular sciences. Volume 25, Issue 19. 2024
- Co-observation of germline pathogenic variants in breast cancer predisposition genes: Results from analysis of the BRIDGES sequencing dataset.. American journal of human genetics. Volume 111, Issue 9, Pages 2059-2069. 2024
- Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification.. medRxiv : the preprint server for health sciences. 2024
- A Novel Dhillonvirus Phage against Escherichia coli Bearing a Unique Gene of Intergeneric Origin.. Current issues in molecular biology. Volume 46, Issue 9, Pages 9312-9329. 2024
- Nanomechanical and Microstructural Characterization of Biocompatible Ti(3)Au Thin Films Grown on Glass and Ti(6)Al(4)V Substrates.. ACS biomaterials science & engineering. Volume 10, Issue 5, Pages 2935-2944. 2024
- Isothiocyanates Potentiate Tazemetostat-Induced Apoptosis by Modulating the Expression of Apoptotic Genes, Members of Polycomb Repressive Complex 2, and Levels of Tri-Methylating Lysine 27 at Histone 3 in Human Malignant Melanoma Cells.. International journal of molecular sciences. Volume 25, Issue 5. 2024
- The Predictive Value of 8-Hydroxy-Deoxyguanosine (8-OHdG) Serum Concentrations in Irradiated Non-Small Cell Lung Carcinoma (NSCLC) Patients.. Biomedicines. Volume 12, Issue 1. 2024
- Naturally Derived Phenethyl Isothiocyanate Modulates Induction of Oxidative Stress via Its N-Acetylated Cysteine Conjugated form in Malignant Melanoma.. Antioxidants (Basel, Switzerland). Volume 13, Issue 1. 2024
- Biocompatible Ti(3)Au-Ag/Cu thin film coatings with enhanced mechanical and antimicrobial functionality.. Biomaterials research. Volume 27, Issue 1, Page 93. 2023
- A Naturally Derived Watercress Flower-Based Phenethyl Isothiocyanate-Enriched Extract Induces the Activation of Intrinsic Apoptosis via Subcellular Ultrastructural and Ca(2+) Efflux Alterations in an In Vitro Model of Human Malignant Melanoma.. Nutrients. Volume 15, Issue 18. 2023
- Multi-gene panel testing and association analysis in Cypriot breast cancer cases and controls.. Frontiers in genetics. Volume 14, Page 1248492. 2023
- Chemical Profiling and Antioxidant and Anti-Amyloid Capacities of Salvia fruticosa Extracts from Greece.. Plants (Basel, Switzerland). Volume 12, Issue 18. 2023
- Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk.. Nature genetics. Volume 55, Issue 9, Pages 1435-1439. 2023
- Multi-functional bioactive silver- and copper-doped diamond-like carbon coatings for medical implants.. Acta biomaterialia. Volume 167, Pages 54-68. 2023
- Novel Iron Chelator SK4 Drives Cytotoxicity through Inhibiting Mitochondrial Metabolism in Ovarian and Triple Negative Breast Cancer Cell Lines.. Biomedicines. Volume 11, Issue 7. 2023
- Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases.. Cancers. Volume 15, Issue 13. 2023
- FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women.. European journal of human genetics : EJHG. Volume 31, Issue 5, Pages 578-587. 2023
- Sideritis scardica Extracts Demonstrate Neuroprotective Activity against Aβ(25-35) Toxicity.. Plants (Basel, Switzerland). Volume 12, Issue 8. 2023
- Chemical Characterization and Biological Evaluation of Epilobium parviflorum Extracts in an In Vitro Model of Human Malignant Melanoma.. Plants (Basel, Switzerland). Volume 12, Issue 8. 2023
- Investigating the Functional Roles of Aldehyde Dehydrogenase 3A1 in Human Corneal Epithelial Cells.. International journal of molecular sciences. Volume 24, Issue 6. 2023
- Observational study of health utilities in adult primary ciliary dyskinesia patients: preliminary data on associations with molecular diagnosis, clinical phenotype and HRQOL measures.. Multidisciplinary respiratory medicine. Volume 17, Page 881. 2022
- Targeting the epigenome in malignant melanoma: Facts, challenges and therapeutic promises.. Pharmacology & therapeutics. Volume 240, Page 108301. 2022
- Chemical Profiling, Antiproliferative and Antimigratory Capacity of Haberlea rhodopensis Extracts in an In Vitro Platform of Various Human Cancer Cell Lines.. Antioxidants (Basel, Switzerland). Volume 11, Issue 12. 2022
- Polyphenolics, glucosinolates and isothiocyanates profiling of aerial parts of Nasturtium officinale (Watercress).. Frontiers in plant science. Volume 13, Page 998755. 2022
- Novel iron chelator SK4 demonstrates cytotoxicity in a range of tumour derived cell lines.. Frontiers in molecular biosciences. Volume 9, Page 1005092. 2022
- Stbd1-deficient mice display insulin resistance associated with enhanced hepatic ER-mitochondria contact.. Biochimie. Volume 200, Pages 172-183. 2022
- A novel lineage-tracing mouse model for studying early MmuPV1 infections.. eLife. Volume 11. 2022
- Effectiveness of Hyperthermia as Monotherapy and Adjuvant Therapy Approaches Against an In Vitro Model of Colorectal Carcinoma.. Anticancer research. Volume 42, Issue 5, Pages 2363-2374. 2022
- Expression of CD47 and SIRPα Macrophage Immune-Checkpoint Pathway in Non-Small-Cell Lung Cancer.. Cancers. Volume 14, Issue 7. 2022
- Assessment of Methodological Pipelines for the Determination of Isothiocyanates Derived from Natural Sources.. Antioxidants (Basel, Switzerland). Volume 11, Issue 4. 2022
- Thermal activation of Ti(1-x)Au(x) thin films with enhanced hardness and biocompatibility.. Bioactive materials. Volume 15, Pages 426-445. 2022
- Cereal and Confectionary Packaging: Background, Application and Shelf-Life Extension.. Foods (Basel, Switzerland). Volume 11, Issue 5. 2022
- Omega-3 fatty acids promote neuroprotection, decreased apoptosis and reduced glial cell activation in the retina of a mouse model of OPA1-related autosomal dominant optic atrophy.. Experimental eye research. Volume 215, Page 108901. 2022
- Evaluation of Bioactive Properties of Lipophilic Fractions of Edible and Non-Edible Parts of Nasturtium officinale (Watercress) in a Model of Human Malignant Melanoma Cells.. Pharmaceuticals (Basel, Switzerland). Volume 15, Issue 2. 2022
- Characterization of IgG Antibody Response against SARS-CoV-2 (COVID-19) in the Cypriot Population.. Microorganisms. Volume 10, Issue 1. 2021
- Benzyl and phenethyl isothiocyanates as promising epigenetic drug compounds by modulating histone acetylation and methylation marks in malignant melanoma.. Investigational new drugs. Volume 39, Issue 6, Pages 1460-1468. 2021
- Chemical and Biological Characterization of the Anticancer Potency of Salvia fruticosa in a Model of Human Malignant Melanoma.. Plants (Basel, Switzerland). Volume 10, Issue 11. 2021
- Profiling of Aldehyde Dehydrogenase Isoforms in In Vitro Formed Tumorspheres.. Anticancer research. Volume 41, Issue 11, Pages 5481-5488. 2021
- Aberrant Mitochondrial Dynamics and Exacerbated Response to Neuroinflammation in a Novel Mouse Model of CMT2A.. International journal of molecular sciences. Volume 22, Issue 21. 2021
- Combination of a 15-SNP Polygenic Risk Score and Classical Risk Factors for the Prediction of Breast Cancer Risk in Cypriot Women.. Cancers. Volume 13, Issue 18. 2021
- A novel methylated analogue of L-Mimosine exerts its therapeutic potency through ROS production and ceramide-induced apoptosis in malignant melanoma.. Investigational new drugs. Volume 39, Issue 4, Pages 971-986. 2021
- Prognostic Relevance of the Relative Presence of CD4, CD8 and CD20 Expressing Tumor Infiltrating Lymphocytes in Operable Non-small Cell Lung Cancer Patients.. Anticancer research. Volume 41, Issue 8, Pages 3989-3995. 2021
- Protective role of taurine against oxidative stress (Review).. Molecular medicine reports. Volume 24, Issue 2. 2021
- Molecular epidemiology of SARS-CoV-2 in Cyprus.. PloS one. Volume 16, Issue 7, Page e0248792. 2021
- Effects of a Novel Thiadiazole Derivative with High Anticancer Activity on Cancer Cell Immunogenic Markers: Mismatch Repair System, PD-L1 Expression, and Tumor Mutation Burden.. Pharmaceutics. Volume 13, Issue 6. 2021
- Ameliorative effect of taurine against diabetes and renal-associated disorders (Review).. Medicine international. Volume 1, Issue 2, Page 3. 2021
- Toxicity Profiling of Biosurfactants Produced by Novel Marine Bacterial Strains.. International journal of molecular sciences. Volume 22, Issue 5. 2021
- An Evaluation of the Anti-Carcinogenic Response of Major Isothiocyanates in Non-Metastatic and Metastatic Melanoma Cells.. Antioxidants (Basel, Switzerland). Volume 10, Issue 2. 2021
- Sulforaphane and iberin are potent epigenetic modulators of histone acetylation and methylation in malignant melanoma.. European journal of nutrition. Volume 60, Issue 1, Pages 147-158. 2021
- Aldehyde Dehydrogenase 1B1 Is Associated with Altered Cell Morphology, Proliferation, Migration and Chemosensitivity in Human Colorectal Adenocarcinoma Cells.. Biomedicines. Volume 9, Issue 1. 2021
- Osteoporosis Entwined with Cardiovascular Disease: The Implication of Osteoprotegerin and the Example of Statins.. Current medicinal chemistry. Volume 28, Issue 7, Pages 1443-1467. 2021
- Mitochondrial Metabolism in Astrocytes Regulates Brain Bioenergetics, Neurotransmission and Redox Balance.. Frontiers in neuroscience. Volume 14, Page 536682. 2020
- Repurposing denosumab in breast cancer beyond prevention of skeletal related events: Could nonclinical data be translated into clinical practice?. Expert review of clinical pharmacology. Volume 13, Issue 11, Pages 1235-1252. 2020
- Significance of taurine transporter (TauT) in homeostasis and its layers of regulation (Review).. Molecular medicine reports. Volume 22, Issue 3, Pages 2163-2173. 2020
- 3,6-Disubstituted 1,2,4-Triazolo[3,4-b]Thiadiazoles with Anticancer Activity Targeting Topoisomerase II Alpha.. OncoTargets and therapy. Volume 13, Pages 7369-7386. 2020
- Surface Active Agents and Their Health-Promoting Properties: Molecules of Multifunctional Significance.. Pharmaceutics. Volume 12, Issue 7. 2020
- Prophylactic lymph node dissection in clinically N0 differentiated thyroid carcinoma: example of personalized treatment.. Personalized medicine. Volume 17, Issue 4, Pages 317-338. 2020
- Honey Extracts Exhibit Cytoprotective Properties against UVB-Induced Photodamage in Human Experimental Skin Models.. Antioxidants (Basel, Switzerland). Volume 9, Issue 7. 2020
- Marine-Derived Surface Active Agents: Health-Promoting Properties and Blue Biotechnology-Based Applications.. Biomolecules. Volume 10, Issue 6. 2020
- Anticancer activity of a novel methylated analogue of L-mimosine against an in vitro model of human malignant melanoma.. Investigational new drugs. Volume 38, Issue 3, Pages 621-633. 2020
- Azasteroid Alkylators as Dual Inhibitors of AKT and ERK Signaling for the Treatment of Ovarian Carcinoma.. Cancers. Volume 12, Issue 5. 2020
- Capecitabine, Oxaliplatin, Irinotecan, and Bevacizumab Combination Followed by Pazopanib Plus Capecitabine Maintenance for High-Grade Gastrointestinal Neuroendocrine Carcinomas.. American journal of clinical oncology. Volume 43, Issue 5, Pages 305-310. 2020
- Endocrine adverse events related with immune checkpoint inhibitors: an update for clinicians.. Immunotherapy. Volume 12, Issue 7, Pages 481-510. 2020
- Aldehyde dehydrogenase 3A1 confers oxidative stress resistance accompanied by altered DNA damage response in human corneal epithelial cells.. Free radical biology & medicine. Volume 150, Pages 66-74. 2020
- Allyl isothiocyanate regulates lysine acetylation and methylation marks in an experimental model of malignant melanoma.. European journal of nutrition. Volume 59, Issue 2, Pages 557-569. 2020
- Redox homeostasis, oxidative stress and mitophagy.. Mitochondrion. Volume 51, Pages 105-117. 2020
- Survival Mechanisms and Xenobiotic Susceptibility of Keratinocytes Exposed to Metal-Derived Nanoparticles.. Chemical research in toxicology. Volume 33, Issue 2, Pages 536-552. 2020
- Harnessing the versatile role of OPG in bone oncology: counterbalancing RANKL and TRAIL signaling and beyond.. Clinical & experimental metastasis. Volume 37, Issue 1, Pages 13-30. 2020
- Combining immune checkpoint inhibitors with denosumab: a new era in repurposing denosumab in oncology?. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. Volume 25, Issue 1, Pages 1-14. 2020
- A Deep Learning Framework for Predicting Response to Therapy in Cancer.. Cell reports. Volume 29, Issue 11, Pages 3367-3373.e4. 2019
- Arsenic-induced neurotoxicity: a mechanistic appraisal.. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. Volume 24, Issue 8, Pages 1305-1316. 2019
- Parathyroid hormone related protein (PTHrP)-mediated hypercalcemia in malignancy associated with anti-PD-1 immune checkpoint inhibitor treatment and related inflammatory reactions.. International immunopharmacology. Volume 77, Page 105942. 2019
- Iridium(iii) complexes of 1,2,4-triazines as potential bioorthogonal reagents: metal coordination facilitates luminogenic reaction with strained cyclooctynes.. Chemical communications (Cambridge, England). Volume 55, Issue 95, Pages 14283-14286. 2019
- Mitochondrial Homeostasis and Cellular Senescence.. Cells. Volume 8, Issue 7. 2019
- Propolis Extracts Inhibit UV-Induced Photodamage in Human Experimental In Vitro Skin Models.. Antioxidants (Basel, Switzerland). Volume 8, Issue 5. 2019
- Hyperthermia Suppresses Post - In Vitro Proliferation and Tumor Growth in Murine Malignant Melanoma and Colon Carcinoma.. Anticancer research. Volume 39, Issue 5, Pages 2307-2315. 2019
- The Role of Isothiocyanates as Cancer Chemo-Preventive, Chemo-Therapeutic and Anti-Melanoma Agents.. Antioxidants (Basel, Switzerland). Volume 8, Issue 4. 2019
- Probiotics in Extraintestinal Diseases: Current Trends and New Directions.. Nutrients. Volume 11, Issue 4. 2019
- DNA-dependent protein kinase: Epigenetic alterations and the role in genomic stability of cancer.. Mutation research. Reviews in mutation research. Volume 780, Pages 92-105. 2019
- Isothiocyanate-induced Cell Cycle Arrest in a Novel In Vitro Exposure Protocol of Human Malignant Melanoma (A375) Cells.. Anticancer research. Volume 39, Issue 2, Pages 591-596. 2019
- Novel Docosahexaenoic Acid Ester of Phloridzin Inhibits Proliferation and Triggers Apoptosis in an In Vitro Model of Skin Cancer.. Antioxidants (Basel, Switzerland). Volume 7, Issue 12. 2018
- Mesenchymal stem cells in preclinical cancer cytotherapy: a systematic review.. Stem cell research & therapy. Volume 9, Issue 1, Page 336. 2018
- Production of a Novel Functional Fruit Beverage Consisting of Cornelian Cherry Juice and Probiotic Bacteria.. Antioxidants (Basel, Switzerland). Volume 7, Issue 11. 2018
- From chemo-prevention to epigenetic regulation: The role of isothiocyanates in skin cancer prevention.. Pharmacology & therapeutics. Volume 190, Pages 187-201. 2018
- CRISPR therapeutic tools for complex genetic disorders and cancer (Review).. International journal of oncology. Volume 53, Issue 2, Pages 443-468. 2018
- Hyperthermia induces therapeutic effectiveness and potentiates adjuvant therapy with non-targeted and targeted drugs in an in vitro model of human malignant melanoma.. Scientific reports. Volume 8, Issue 1, Page 10724. 2018
- Chemical Composition and Evaluation of the Biological Properties of the Essential Oil of the Dietary Phytochemical Lippia citriodora.. Molecules (Basel, Switzerland). Volume 23, Issue 1. 2018
- Role of the CRISPR system in controlling gene transcription and monitoring cell fate (Review).. Molecular medicine reports. Volume 17, Issue 1, Pages 1421-1427. 2018
- Mitochondrial dysfunction in glial cells: Implications for neuronal homeostasis and survival.. Toxicology. Volume 391, Pages 109-115. 2017
- Gold nanoparticles, radiations and the immune system: Current insights into the physical mechanisms and the biological interactions of this new alliance towards cancer therapy.. Pharmacology & therapeutics. Volume 178, Pages 1-17. 2017
- Human aldehyde dehydrogenase 3A1 (ALDH3A1) exhibits chaperone-like function.. The international journal of biochemistry & cell biology. Volume 89, Pages 16-24. 2017
- Glucose Metabolism and AMPK Signaling Regulate Dopaminergic Cell Death Induced by Gene (α-Synuclein)-Environment (Paraquat) Interactions.. Molecular neurobiology. Volume 54, Issue 5, Pages 3825-3842. 2017
- Metabolic Dysfunction in Parkinson's Disease: Bioenergetics, Redox Homeostasis and Central Carbon Metabolism.. Brain research bulletin. Volume 133, Pages 12-30. 2017
- Dietary mastic oil extracted from Pistacia lentiscus var. chia suppresses tumor growth in experimental colon cancer models.. Scientific reports. Volume 7, Issue 1, Page 3782. 2017
- Metabolic Investigations of the Molecular Mechanisms Associated with Parkinson's Disease.. Metabolites. Volume 7, Issue 2. 2017
- A Novel Role of Silibinin as a Putative Epigenetic Modulator in Human Prostate Carcinoma.. Molecules (Basel, Switzerland). Volume 22, Issue 1. 2016
- Development of a Novel Experimental In Vitro Model of Isothiocyanate-induced Apoptosis in Human Malignant Melanoma Cells.. Anticancer research. Volume 36, Issue 12, Pages 6303-6309. 2016
- Antioxidant and Antiproliferative Properties of the Essential Oils of Satureja thymbra and Satureja parnassica and their Major Constituents.. Anticancer research. Volume 36, Issue 11, Pages 5757-5763. 2016
- Phytochemicals in regulating fatty acid β-oxidation: Potential underlying mechanisms and their involvement in obesity and weight loss.. Pharmacology & therapeutics. Volume 165, Pages 153-63. 2016
- Phytochemical Profile and Evaluation of the Biological Activities of Essential Oils Derived from the Greek Aromatic Plant Species Ocimum basilicum, Mentha spicata, Pimpinella anisum and Fortunella margarita.. Molecules (Basel, Switzerland). Volume 21, Issue 8. 2016
- Aldehyde dehydrogenase 3A1 promotes multi-modality resistance and alters gene expression profile in human breast adenocarcinoma MCF-7 cells.. The international journal of biochemistry & cell biology. Volume 77, Issue Pt A, Pages 120-128. 2016
- Effects of hyperthermia as a mitigation strategy in DNA damage-based cancer therapies.. Seminars in cancer biology. Volume 37-38, Pages 96-105. 2016
- The DNA damage response and immune signaling alliance: Is it good or bad? Nature decides when and where.. Pharmacology & therapeutics. Volume 154, Pages 36-56. 2015
- Epigenetic therapy as a novel approach in hepatocellular carcinoma.. Pharmacology & therapeutics. Volume 145, Pages 103-19. 2015
- In-vitro assessment of Jurkat T-cells response to 1966 MHz electromagnetic fields in a GTEM cell.. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. Volume 2015, Pages 2592-5. 2015
- Non-targeted radiation effects in vivo: a critical glance of the future in radiobiology.. Cancer letters. Volume 356, Issue 1, Pages 34-42. 2015
- Oxidative stress, redox signaling, and autophagy: cell death versus survival.. Antioxidants & redox signaling. Volume 21, Issue 1, Pages 66-85. 2014
- Silibinin protects H9c2 cardiac cells from oxidative stress and inhibits phenylephrine-induced hypertrophy: potential mechanisms.. The Journal of nutritional biochemistry. Volume 24, Issue 3, Pages 586-94. 2013
- Efficient E. coli expression strategies for production of soluble human crystallin ALDH3A1.. PloS one. Volume 8, Issue 2, Page e56582. 2013
- Molecular markers for cancer prognosis and treatment: have we struck gold?. Cancer letters. Volume 327, Issue 1-2, Pages 142-52. 2012
- Pleiotrophic effects of natural products in ROS-induced carcinogenesis: the role of plant-derived natural products in oral cancer chemoprevention.. Cancer letters. Volume 327, Issue 1-2, Pages 16-25. 2012
- Biomarkers of protein oxidation in human disease.. Current molecular medicine. Volume 12, Issue 6, Pages 681-97. 2012
- Oxidative stress based-biomarkers in oral carcinogenesis: how far have we gone?. Current molecular medicine. Volume 12, Issue 6, Pages 698-703. 2012
- Biochemical and molecular analysis of the interaction between ERK2 MAP kinase and hypoxia inducible factor-1α.. The international journal of biochemistry & cell biology. Volume 43, Issue 11, Pages 1582-90. 2011
- DNA damage and autophagy.. Mutation research. Volume 711, Issue 1-2, Pages 158-66. 2011
- DNA damage induced by endogenous aldehydes: current state of knowledge.. Mutation research. Volume 711, Issue 1-2, Pages 13-27. 2011
- Reactive oxygen species (ROS)--induced genetic and epigenetic alterations in human carcinogenesis.. Mutation research. Volume 711, Issue 1-2, Pages 167-73. 2011
- Molecular mechanisms of pesticide-induced neurotoxicity: Relevance to Parkinson's disease.. Chemico-biological interactions. Volume 188, Issue 2, Pages 289-300. 2010
- The role of epigenetics in environmental and occupational carcinogenesis.. Chemico-biological interactions. Volume 188, Issue 2, Pages 340-9. 2010
- The role of reactive oxygen species and oxidative stress in environmental carcinogenesis and biomarker development.. Chemico-biological interactions. Volume 188, Issue 2, Pages 334-9. 2010
- Ouabain-induced perturbations in intracellular ionic homeostasis regulate death receptor-mediated apoptosis.. Apoptosis : an international journal on programmed cell death. Volume 15, Issue 7, Pages 834-49. 2010
- Viral-induced human carcinogenesis: an oxidative stress perspective.. Molecular bioSystems. Volume 6, Issue 7, Pages 1162-72. 2010
- DNA-PKcs deficiency leads to persistence of oxidatively induced clustered DNA lesions in human tumor cells.. Free radical biology & medicine. Volume 48, Issue 10, Pages 1435-43. 2010
- BRCA1 involvement in toxicological responses and human cancer etiology.. Toxicology letters. Volume 188, Issue 2, Pages 77-83. 2009
- Accumulation of oxidatively induced clustered DNA lesions in human tumor tissues.. Mutation research. Volume 674, Issue 1-2, Pages 131-6. 2009
- Compromised repair of clustered DNA damage in the human acute lymphoblastic leukemia MSH2-deficient NALM-6 cells.. Mutation research. Volume 674, Issue 1-2, Pages 123-30. 2009
- Environmental toxicity, oxidative stress and apoptosis: ménage à trois.. Mutation research. Volume 674, Issue 1-2, Pages 3-22. 2009
- Oxidative stress-induced regulation of the methionine metabolic pathway in human lung epithelial-like (A549) cells.. Mutation research. Volume 674, Issue 1-2, Pages 23-30. 2009
- Processing of clustered DNA damage in human breast cancer cells MCF-7 with partial DNA-PKcs deficiency.. Cancer letters. Volume 269, Issue 1, Pages 174-83. 2008
- Oxidative stress, DNA methylation and carcinogenesis.. Cancer letters. Volume 266, Issue 1, Pages 6-11. 2008
- Autocrine signaling involved in cell volume regulation: the role of released transmitters and plasma membrane receptors.. Journal of cellular physiology. Volume 216, Issue 1, Pages 14-28. 2008
- Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation.. The Journal of biological chemistry. Volume 282, Issue 42, Pages 30452-65. 2007
- The central role of glutathione in the pathophysiology of human diseases.. Archives of physiology and biochemistry. Volume 113, Issue 4-5, Pages 234-58. 2007
- Sulfur-containing compounds in protecting against oxidant-mediated lung diseases.. Current medicinal chemistry. Volume 14, Issue 24, Pages 2590-6. 2007
- Effect of cell cycle growth arrest on global DNA methylation status in human lung epithelial-like (A549) cells.. In vivo (Athens, Greece). Volume 20, Issue 6B, Pages 861-5. 2006
- On the mechanism of ionic regulation of apoptosis: would the Na+/K+-ATPase please stand up?. Acta physiologica (Oxford, England). Volume 187, Issue 1-2, Pages 205-15. 2006
- Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia.. Free radical biology & medicine. Volume 40, Issue 2, Pages 348-58. 2006
- Hyperoxia-induced DNA damage causes decreased DNA methylation in human lung epithelial-like A549 cells.. Antioxidants & redox signaling. Volume 6, Issue 1, Pages 129-36. 2004
- Cigarette smoke extract increases S-adenosylmethionine and cystathionine in human lung epithelial-like (A549) cells.. Chemico-biological interactions. Volume 147, Issue 1, Pages 87-97. 2004
- Glucose oxidase-produced H2O2 induces Ca2+-dependent DNA damage in human peripheral blood lymphocytes.. Free radical biology & medicine. Volume 26, Issue 5-6, Pages 548-56. 1999
- Ex vivo assessment of lymphocyte antioxidant status using the comet assay.. Free radical research. Volume 27, Issue 5, Pages 533-7. 1997
- Comet assay in human biomonitoring studies: reliability, validation, and applications.. Environmental and molecular mutagenesis. Volume 30, Issue 2, Pages 139-46. 1997
Published Erratum
- Author Correction: Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk.. Nature genetics. Volume 55, Issue 11, Page 2009. 2023
Areas of Expertise
Cancer Epigenetics Cancer Therapeutics Drug Development / Repurposing Natural Products / Phytochemicals Disease Biomarkers Novel Engineered Materials / Biomedical Applications